Brain cells

Scientists reveal sex-specific cognitive effects of astrocyte receptors

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Scientists at Weill Cornell Medicine have discovered groundbreaking evidence that astrocyte receptors can have opposite effects on cognitive function in male and female preclinical models. This finding highlights the significant role of astrocytes—brain cells that support and regulate neurons—in sex-specific brain mechanisms. Traditionally, studies have focused on the behavioral effects of astrocytic receptors, predominantly in … Read more

Study reveals surprising dynamics of brain blood flow

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For the first time, researchers have successfully visualized the intricate network of blood vessels spanning the cortex of awake mice. Their groundbreaking observations revealed that these blood vessels rhythmically expand and contract, creating “waves” that wash across the brain’s surface. This discovery, published in the journal Neuron, significantly enhances our understanding of cerebral blood flow, … Read more

Study shows nerve stimulation boosts brain-boosting molecule release from muscle

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Exercise prompts muscles to release molecular cargo that boosts brain cell function and connection, but the process is not well understood. New research from the University of Illinois Urbana-Champaign has found that the nerves that tell muscles to move also prompt them to release more of the brain-boosting factors. “The molecules released from the muscle … Read more

Scientists create mice with hybrid brains

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If mice ever wonder what it’s like to experience the world as a rat, some are now able to live that dream, at least when it comes to the sense of smell. Researchers led by Columbia University’s Kristin Baldwin have created mice with hybrid brains—part mouse, part rat—that sense the odors of the world with … Read more

Neuroscientists propose framework for understanding cognition through brain rhythms

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It could be very informative to observe the pixels on your phone under a microscope, but not if your goal is to understand what a whole video on the screen shows. Cognition is much the same kind of emergent property in the brain. It can only be understood by observing how millions of cells act … Read more

Study explores CBN’s potential for treating neurological disorders

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One in every 10 individuals above the age of 65 develops an age-related neurological disorder like Alzheimer’s or Parkinson’s, yet treatment options remain sparse for this population. Scientists have begun exploring whether cannabinoids—compounds derived from the cannabis plant, like well-known THC (tetrahydrocannabinol) and CBD (cannabidiol)—may offer a solution. A third, lesser-known cannabinoid called CBN (cannabinol) … Read more

Brain cells work in tandem to regulate goal-oriented behavior in mice

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Hunger can drive a motivational state that leads an animal to a successful pursuit of a goal—foraging for and finding food. In a highly novel study published in Current Biology, researchers at the University of Alabama at Birmingham and the National Institute of Mental Health, or NIMH, describe how two major neuronal subpopulations in a … Read more