Receptors

Study discovers promising immune response for early ovarian cancer diagnosis

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Researchers at Children’s Hospital of Philadelphia (CHOP) announced the discovery of a novel immune-based biomarker that could pave the way for potential lifesaving early detection of high-grade ovarian cancer (HGOC). The findings were published today in the journal Cell Reports Medicine. High-grade ovarian cancer (HGOC) is the fifth-leading cause of cancer-related death among women. More than 90% of … Read more

Researchers discover mechanism disrupting cell signaling pathways

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A group of researchers at University of California San Diego has identified the cause of a “short-circuit” in cellular pathways, a discovery that sheds new light on the genesis of a number of human diseases. The recent study, published in the journal Science Signaling, explores the biochemical mechanism that can interrupt the cellular communication chain—a … Read more

Scientists reveal sex-specific cognitive effects of astrocyte receptors

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Scientists at Weill Cornell Medicine have discovered groundbreaking evidence that astrocyte receptors can have opposite effects on cognitive function in male and female preclinical models. This finding highlights the significant role of astrocytes—brain cells that support and regulate neurons—in sex-specific brain mechanisms. Traditionally, studies have focused on the behavioral effects of astrocytic receptors, predominantly in … Read more

How brain activation affects behavior

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Our brains are made of tens of billions of nerve cells called neurons. These cells communicate with each other through biomolecules called neurotransmitters. Serotonin, a type of neurotransmitter, is produced by serotonin neurons in our brains and influences many of our behavioral and cognitive functions such as memory, sleep, and mood. Using mice, scientists at … Read more

The Role of Sweet Taste Receptors in Metabolic Regulation

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The Monell Chemical Senses Center has long been at the forefront of research into sweet taste, tracing back to 2001 when Monell scientists were among the first to identify and describe the mammalian sweet taste receptor, TAS1R2-TAS1R3. Over the past two decades, Monell researchers have significantly advanced our understanding of the genetics and functionality of … Read more

Systems Biology: Integrating Biological Processes into Complex Systems

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Systems biology is an interdisciplinary field that seeks to understand biological systems as integrated networks of components, processes, and interactions, rather than isolated parts. It combines principles from biology, mathematics, computer science, engineering, and other disciplines to analyze complex biological phenomena at multiple scales, from molecular and cellular levels to tissues, organs, organisms, populations, and … Read more

Neuroplasticity: Brain’s Ability to Change and Adapt

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Neuroplasticity, also known as brain plasticity or neural plasticity, is a fundamental property of the brain that refers to its ability to change and adapt throughout life in response to experiences, learning, environmental stimuli, injury, and disease. This remarkable capacity for structural and functional reorganization enables the brain to modify neural pathways, establish new connections, … Read more

Pharmacology: Study of Drug Action and Interaction with Organisms

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Pharmacology is a multifaceted scientific discipline that delves into the study of drugs, their actions within biological systems, and their interactions with living organisms. It is a field that intersects with various branches of biology, chemistry, medicine, and pharmacy, aiming to understand how drugs work, their therapeutic effects, potential side effects, and mechanisms of action. … Read more

Neurochemistry: Chemical Processes in the Nervous System

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Neurochemistry is the branch of neuroscience that focuses on the chemical processes occurring within the nervous system, including the synthesis, release, reuptake, and metabolism of neurotransmitters, neuromodulators, and other signaling molecules. It encompasses the study of molecular mechanisms underlying neuronal communication, synaptic transmission, neuroplasticity, and brain function. Understanding neurochemistry is essential for unraveling the molecular … Read more

Immunotherapy: Harnessing the Immune System for Disease Treatment

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Immunotherapy represents a revolutionary approach to disease treatment that harnesses the power of the immune system to combat various ailments, including cancer, autoimmune disorders, infectious diseases, and allergies. Unlike traditional treatments such as chemotherapy or surgery, which directly target the disease, immunotherapy works by stimulating or enhancing the body’s immune response to recognize and destroy … Read more

Genetics of Cancer: Causes and Treatments

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Cancer is a complex group of diseases characterized by uncontrolled cell growth and proliferation. It can affect virtually any part of the body and is caused by a combination of genetic, environmental, and lifestyle factors. The genetics of cancer play a crucial role in understanding its causes, development, progression, and potential treatments. Genetic Basis of … Read more

Endocrinology: Study of Hormones and Endocrine System

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Endocrinology is the branch of biology and medicine that deals with the study of hormones and the endocrine system. Hormones are chemical messengers produced by glands in the endocrine system, which regulate various physiological processes and maintain homeostasis in the body. The endocrine system consists of glands and organs that secrete hormones directly into the … Read more

Molecular Biology: Understanding Biological Processes at the Molecular Level

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Molecular biology is a branch of biology that explores the structure, function, and interactions of biomolecules, such as DNA, RNA, proteins, lipids, and carbohydrates, at the molecular level. It encompasses a wide range of techniques, methodologies, and disciplines aimed at understanding biological processes, genetic information flow, gene expression, cellular functions, and molecular mechanisms underlying life. … Read more

Botany: Diversity and Adaptations of Plants

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Botany, the scientific study of plants, encompasses a vast array of topics ranging from plant structure and function to their evolutionary history, ecological interactions, and economic importance. Plants are essential for life on Earth, serving as the primary producers in ecosystems, providing oxygen, food, shelter, and numerous other resources for humans and other organisms. The … Read more

Study shows sunflowers recruit microbes to fight off fungal disease

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Sunflowers aren’t just beautiful symbols of summer—they are also economically significant, ranking as the fourth most important oilseed crop in the world, and new research suggests that some bacteria might help protect the crop from white-mold destruction. Sunflowers can be harvested for a number of products including seeds and oil, for which consumer demand has … Read more

Plant Physiology: Adaptations and Growth Mechanisms

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Plant physiology is the branch of biology that focuses on the study of how plants function, grow, develop, and respond to their environment. It encompasses a wide range of topics, including plant anatomy, biochemistry, metabolism, genetics, reproduction, and interactions with biotic and abiotic factors. Understanding plant physiology is essential for agriculture, forestry, ecology, environmental science, … Read more

Virology: Study of Viruses and Viral Diseases

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Virology is the scientific study of viruses, their structure, function, evolution, and interactions with host organisms. Viruses are microscopic infectious agents that can infect a wide range of living organisms, from bacteria and archaea to plants, animals, and humans. They are unique entities that straddle the boundary between living and non-living, as they require host … Read more

Neurobiology: Exploring the Nervous System

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Neurobiology is a fascinating field of study that delves into the intricacies of the nervous system, which serves as the body’s communication and control center. The nervous system is a complex network of cells, tissues, and organs that coordinate sensory perception, motor function, cognition, and behavior. In this exploration of neurobiology, we will delve into … Read more

Immunology: The Body’s Defense Mechanisms

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Immunology is the branch of biomedical science that focuses on the study of the immune system, which is the body’s intricate network of organs, tissues, cells, and molecules that work together to defend against pathogens, foreign substances, and abnormal cells. The immune system plays a vital role in maintaining health and protecting the body from … Read more

Physiology: Functions of Organ Systems

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Physiology is the branch of biology that focuses on the study of the functions and processes of living organisms and their parts. It encompasses various levels of organization, from cells and tissues to organs and organ systems, and examines how these components work together to maintain homeostasis and support life. In this discussion, we’ll delve … Read more