Infectious diseases

Microbial Genetics: Genetic Mechanisms in Bacteria and Archaea

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Microbial genetics is a specialized field within genetics that focuses on the study of genetic mechanisms in bacteria and archaea, collectively referred to as microorganisms or microbes. These single-celled organisms play crucial roles in various ecosystems, contributing to nutrient cycling, biogeochemical processes, symbiotic relationships, and human health. Microbial genetics explores the diversity, evolution, regulation, and … Read more

Systems Biology: Integrating Biological Processes into Complex Systems

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Systems biology is an interdisciplinary field that seeks to understand biological systems as integrated networks of components, processes, and interactions, rather than isolated parts. It combines principles from biology, mathematics, computer science, engineering, and other disciplines to analyze complex biological phenomena at multiple scales, from molecular and cellular levels to tissues, organs, organisms, populations, and … Read more

Microbial Ecology: Roles of Microorganisms in Ecosystems

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Microbial ecology is the branch of ecology that studies the interactions between microorganisms and their environment, including other organisms, abiotic factors, and biogeochemical processes. Microorganisms, including bacteria, archaea, fungi, protists, and viruses, play essential roles in ecosystem dynamics, nutrient cycling, energy flow, and biogeochemical transformations. Understanding microbial ecology is crucial for elucidating the functioning of … Read more

Epidemiology: Study of Disease Patterns and Spread

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Epidemiology is the study of the distribution and determinants of health-related states or events in populations and the application of this study to control health problems. It is a cornerstone of public health, providing insights into the patterns, causes, and impacts of diseases within populations. Epidemiologists investigate the occurrence of diseases, injuries, disabilities, and deaths, … Read more

Immunotherapy: Harnessing the Immune System for Disease Treatment

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Immunotherapy represents a revolutionary approach to disease treatment that harnesses the power of the immune system to combat various ailments, including cancer, autoimmune disorders, infectious diseases, and allergies. Unlike traditional treatments such as chemotherapy or surgery, which directly target the disease, immunotherapy works by stimulating or enhancing the body’s immune response to recognize and destroy … Read more

Zoology: Diversity and Classification of Animals

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Zoology is the branch of biology that focuses on the study of animals, their behavior, physiology, classification, evolution, and distribution. It encompasses a vast array of organisms, from microscopic protozoa to large mammals, and explores the diversity of life on Earth. Zoologists investigate the structure, function, ecology, and behavior of animals in order to understand … Read more

Virology: Study of Viruses and Viral Diseases

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Virology is the scientific study of viruses, their structure, function, evolution, and interactions with host organisms. Viruses are microscopic infectious agents that can infect a wide range of living organisms, from bacteria and archaea to plants, animals, and humans. They are unique entities that straddle the boundary between living and non-living, as they require host … Read more

Biotechnology: Applications in Medicine and Industry

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Biotechnology is a rapidly evolving field that harnesses biological processes and systems to develop innovative solutions for various applications in medicine and industry. It encompasses a diverse range of techniques, including genetic engineering, fermentation, and cell culture, to manipulate biological systems for practical purposes. Biotechnology has revolutionized healthcare, agriculture, environmental science, and industrial manufacturing, offering … Read more

DNA Structure and Function: Blueprint of Life

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DNA (deoxyribonucleic acid) is a molecule that serves as the blueprint of life, carrying the genetic instructions necessary for the growth, development, functioning, and reproduction of all living organisms. Its structure and function are essential components of molecular biology and genetics, providing insights into the fundamental processes that govern life on Earth. DNA Structure The … Read more

Microbiology: The World of Microscopic Organisms

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Microbiology is the branch of biology that explores the world of microscopic organisms, including bacteria, viruses, fungi, protozoa, and algae. These tiny life forms, invisible to the naked eye, play essential roles in ecosystems, human health, agriculture, industry, and environmental processes. Microbiology encompasses diverse areas of study, from microbial diversity and evolution to microbial ecology, … Read more

Evolutionary Theory: Darwin’s Legacy in Biology

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Evolutionary theory, anchored in Charles Darwin’s seminal work “On the Origin of Species,” represents one of the most profound and influential concepts in the history of biology. Darwin’s theory revolutionized our understanding of the natural world, providing a unifying framework for explaining the diversity of life, the mechanisms of evolutionary change, and the interconnectedness of … Read more

NIH trial shows single-dose monoclonal antibody highly effective against malaria in children

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One injected dose of an experimental malaria monoclonal antibody was 77% effective against malaria disease in children in Mali during the country’s six-month malaria season, according to the results of a mid-stage clinical trial. The trial assessed an investigational monoclonal antibody developed by scientists at the National Institutes of Health (NIH), and results appear in … Read more

Loss of IgA antibodies identified as cause of post-stroke/heart attack immunodeficiency

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Every year, between 250,000 and 300,000 people in Germany suffer from a stroke or heart attack. These patients suffer immune disturbances and are very frequently susceptible to life-threatening bacterial infections. Until now, little was known about the underlying mechanisms of this immune dysfunction. Research teams from the Faculty of Medicine at the University Hospital of … Read more

University of Tokyo develops improved mid-infrared microscope with 120 nanometer resolution

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A team at the University of Tokyo have constructed an improved mid-infrared microscope, enabling them to see the structures inside living bacteria at the nanometer scale. Mid-infrared microscopy is typically limited by its low resolution, especially when compared to other microscopy techniques. Their work has been published in Nature Photonics. This latest development produced images at 120 nanometers, … Read more

Bioarchaeological analysis reveals widespread violence during Central Andean Formative period

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The transition from the fifth to the fourth century BCE (Before the Common Era) seems to have been a critical period for the Central Andes, a region now part of Peru. Researchers have found evidence of turbulence during the passage from the Middle Formative period (1200–400 BCE) to the Late Formative period (400–1 BCE). Political … Read more

Scientists unveil key protein interaction in Ebola virus replication

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Scientists from multiple institutions in North America have achieved a significant milestone in unraveling the mechanisms underlying Ebola virus replication within human cells. This breakthrough marks a crucial advancement towards the creation of novel treatments aimed at tackling this formidable and often fatal illness. The study, published in PLOS Biology, involved a team of pharmacologists … Read more

New COVID vaccine offers broader protection against omicron variants

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Researchers at the Francis Crick Institute and the National Institute for Health and Care Research Biomedical Research Centre at UCLH have highlighted the importance of continued surveillance of emerging SARS-CoV-2 variants and vaccine performance as the virus continues to evolve. Published today as a research letter in The Lancet, their study compared the newer monovalent … Read more

Bioarchaeology and its importance in understanding past human societies

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Bioarchaeology is a fascinating interdisciplinary field that combines principles from archaeology, anthropology, biology, and other related disciplines to study human remains from archaeological contexts. By analyzing skeletal remains, bioarchaeologists gain insights into past human populations, their lifeways, health, diet, migration patterns, social structures, and cultural practices. Through a meticulous examination of bones, teeth, and other … Read more

New study suggests potential to shorten treatment duration for drug-resistant TB

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Patients who have drug-resistant tuberculosis (TB) have a similar microbiological response to bedaquiline-based second-line medications as patients with drug-sensitive TB taking first-line regimens, according to researchers at Weill Cornell Medicine in New York and GHESKIO Centers in Haiti. Second-line medications are those that are given when one or more of the drugs given first for … Read more

RNA Polymerase

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RNA polymerase is a key enzyme involved in the process of transcription, where genetic information encoded in DNA is transcribed into RNA molecules. This enzyme plays a crucial role in gene expression, as it catalyzes the synthesis of RNA strands complementary to a DNA template strand. Through its intricate structure and precise mechanism of action, … Read more