Immune response

Study discovers promising immune response for early ovarian cancer diagnosis

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Researchers at Children’s Hospital of Philadelphia (CHOP) announced the discovery of a novel immune-based biomarker that could pave the way for potential lifesaving early detection of high-grade ovarian cancer (HGOC). The findings were published today in the journal Cell Reports Medicine. High-grade ovarian cancer (HGOC) is the fifth-leading cause of cancer-related death among women. More than 90% of … Read more

Human monoclonal antibodies show promise as treatment and prevention for influenza B

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Researchers at Vanderbilt University Medical Center (VUMC) have made a significant breakthrough by isolating human monoclonal antibodies against influenza B. This virus is a notable public health threat, particularly affecting children, the elderly, and individuals with weakened immune systems. While seasonal flu vaccines provide coverage against both influenza A and B, they do not always … Read more

How viruses could become the next cancer treatment

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In the global quest for effective cancer treatments, researchers are uncovering promising strategies in the most unexpected of places: the very viruses we typically strive to avoid. Pathogens such as the common cold and influenza, once seen solely as threats to our health, are now being studied for their potential to target and destroy cancer … Read more

Immunotherapy: Harnessing the Immune System for Disease Treatment

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Immunotherapy represents a revolutionary approach to disease treatment that harnesses the power of the immune system to combat various ailments, including cancer, autoimmune disorders, infectious diseases, and allergies. Unlike traditional treatments such as chemotherapy or surgery, which directly target the disease, immunotherapy works by stimulating or enhancing the body’s immune response to recognize and destroy … Read more

Genetics of Cancer: Causes and Treatments

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Cancer is a complex group of diseases characterized by uncontrolled cell growth and proliferation. It can affect virtually any part of the body and is caused by a combination of genetic, environmental, and lifestyle factors. The genetics of cancer play a crucial role in understanding its causes, development, progression, and potential treatments. Genetic Basis of … Read more

Virology: Study of Viruses and Viral Diseases

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Virology is the scientific study of viruses, their structure, function, evolution, and interactions with host organisms. Viruses are microscopic infectious agents that can infect a wide range of living organisms, from bacteria and archaea to plants, animals, and humans. They are unique entities that straddle the boundary between living and non-living, as they require host … Read more

Cellular Respiration: Energy Production in Cells

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Cellular respiration is a fundamental biological process that occurs in living cells to generate energy in the form of adenosine triphosphate (ATP). This process involves the breakdown of organic molecules, such as glucose, through a series of biochemical reactions that release energy stored in chemical bonds. Cellular respiration is essential for the survival and functioning … Read more

Immunology: The Body’s Defense Mechanisms

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Immunology is the branch of biomedical science that focuses on the study of the immune system, which is the body’s intricate network of organs, tissues, cells, and molecules that work together to defend against pathogens, foreign substances, and abnormal cells. The immune system plays a vital role in maintaining health and protecting the body from … Read more

Physiology: Functions of Organ Systems

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Physiology is the branch of biology that focuses on the study of the functions and processes of living organisms and their parts. It encompasses various levels of organization, from cells and tissues to organs and organ systems, and examines how these components work together to maintain homeostasis and support life. In this discussion, we’ll delve … Read more

Mac-1 inhibitor compound shows promise in blocking SARS-CoV-2 replication in cell cultures

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Research appearing in the Journal of Medicinal Chemistry shows for the first time SARS-CoV-2, the virus responsible for COVID-19, can be inhibited from replicating in living cell cultures using a compound that targets “Mac-1,” a protein key to defending SARS-CoV-2 against the human immune response. University of Kansas researchers in the lab of Anthony Fehr, associate professor … Read more

Blood biomarker identified for early detection of multiple sclerosis

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In a discovery that could hasten treatment for patients with multiple sclerosis (MS), UC San Francisco scientists have discovered a harbinger in the blood of some people who later went on to develop the disease. In about 1 in 10 cases of MS, the body begins producing a distinctive set of antibodies against its own … Read more

New technique revives decades-old cancer samples for immune response studies

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Scientists have developed an improved technique for reading the genetic material associated with the body’s immune response to cancer, making it possible to study tissue samples that have been stored in archives for decades. Using this technique, which is much more sensitive than commercial equivalents and less costly, researchers are able to analyze archival cancer … Read more

New molecule shows promise in targeting SCLC cells and boosting immunity

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A molecule has demonstrated its ability to kill tumor cells and incite an immune response in preclinical models of small cell lung cancer (SCLC), according to UT Southwestern Medical Center researchers. The findings, published in Nature Communications, could lead to more successful treatments for SCLC, one of the leading causes of cancer-related deaths in the … Read more

Scientists develop Zika-based therapy for brain cancer with reduced risk to healthy cells

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Scientists from Duke-NUS Medical School (Duke-NUS) have developed a new approach using the Zika virus to destroy brain cancer cells and inhibit tumor growth, while sparing healthy cells. Using Zika virus vaccine candidates developed at Duke-NUS, the team discovered how these strains target rapidly proliferating cells over mature cells—making them an ideal option to target … Read more

Fungi pass advantageous chromosomes horizontally for enhanced pest control

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Researchers at the Kiel Evolution Center have investigated for the first time in detail how a fungus important for biological plant protection can pass on an advantageous chromosome horizontally, using a previously little-studied way of exchanging genetic information. Sustainable plant protection measures that are not based on chemical pesticides rely on various organisms and biological … Read more

Study finds evidence of long-term COVID-19 antigens in blood and tissue

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New discoveries emerging from UC San Francisco illuminate the persistent presence of the COVID-19 virus in patients’ blood and tissues long after the acute phase of the illness has passed, offering fresh insights into the enigmatic phenomenon of long COVID. In a groundbreaking investigation spearheaded by Dr. Michael Peluso of the UCSF School of Medicine, … Read more

Study links persistent UTI pain to nerve cell overgrowth in bladder

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A perplexing problem for people with recurring urinary tract infections (UTIs) is persistent pain, even after antibiotics have successfully cleared the bacteria. Now Duke Health researchers have identified the likely cause—an overgrowth of nerve cells in the bladder. The finding, appearing March 1 in the journal Science Immunology, provides a potential new approach to managing … Read more