A team from the Innovative Genomics Institute at the University of California, Berkeley (UCB) has produced an increase in gene expression in a food crop by changing its upstream regulatory DNA. While other studies have used CRISPR/Cas9 gene-editing to knock out or decrease the expression of genes, new research published in Science Advances is the … Read more
Microbial genetics is a specialized field within genetics that focuses on the study of genetic mechanisms in bacteria and archaea, collectively referred to as microorganisms or microbes. These single-celled organisms play crucial roles in various ecosystems, contributing to nutrient cycling, biogeochemical processes, symbiotic relationships, and human health. Microbial genetics explores the diversity, evolution, regulation, and … Read more
Systems biology is an interdisciplinary field that seeks to understand biological systems as integrated networks of components, processes, and interactions, rather than isolated parts. It combines principles from biology, mathematics, computer science, engineering, and other disciplines to analyze complex biological phenomena at multiple scales, from molecular and cellular levels to tissues, organs, organisms, populations, and … Read more
Evolutionary genetics is a field of study that explores genetic changes within populations and species over generations, elucidating the mechanisms and processes driving evolutionary processes. It integrates principles from genetics, molecular biology, population genetics, and evolutionary biology to understand how genetic variation, mutation, natural selection, genetic drift, gene flow, and other factors shape the genetic … Read more
Gene editing technologies have revolutionized the field of molecular biology and genetics by providing powerful tools to precisely modify DNA sequences, study gene functions, correct genetic mutations, and engineer biological systems. Among the most widely used and transformative gene editing technologies is CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and its associated protein, Cas (CRISPR-associated … Read more
Bioinformatics is a multidisciplinary field that combines biology, computer science, mathematics, and statistics to analyze and interpret biological data. It plays a crucial role in advancing our understanding of complex biological systems, from genomics and proteomics to evolutionary biology and drug discovery. By leveraging computational tools and algorithms, bioinformatics enables researchers to extract meaningful insights … Read more
Molecular biology is a branch of biology that explores the structure, function, and interactions of biomolecules, such as DNA, RNA, proteins, lipids, and carbohydrates, at the molecular level. It encompasses a wide range of techniques, methodologies, and disciplines aimed at understanding biological processes, genetic information flow, gene expression, cellular functions, and molecular mechanisms underlying life. … Read more
Biotechnology is a rapidly evolving field that harnesses biological processes and systems to develop innovative solutions for various applications in medicine and industry. It encompasses a diverse range of techniques, including genetic engineering, fermentation, and cell culture, to manipulate biological systems for practical purposes. Biotechnology has revolutionized healthcare, agriculture, environmental science, and industrial manufacturing, offering … Read more
DNA (deoxyribonucleic acid) is a molecule that serves as the blueprint of life, carrying the genetic instructions necessary for the growth, development, functioning, and reproduction of all living organisms. Its structure and function are essential components of molecular biology and genetics, providing insights into the fundamental processes that govern life on Earth. DNA Structure The … Read more
Microbiology is the branch of biology that explores the world of microscopic organisms, including bacteria, viruses, fungi, protozoa, and algae. These tiny life forms, invisible to the naked eye, play essential roles in ecosystems, human health, agriculture, industry, and environmental processes. Microbiology encompasses diverse areas of study, from microbial diversity and evolution to microbial ecology, … Read more
Genetics, the study of heredity and the molecular basis of life, represents a cornerstone of modern biology with profound implications for understanding biological diversity, human health, evolution, and biotechnological applications. At the core of genetics lies the exploration of genetic inheritance, the transmission of traits from parents to offspring, and the molecular mechanisms governing genetic … Read more
In a striking new study published in Science Advances, a team of synthetic biologists led by Karen Sarkisyan at the MRC Laboratory of Medical Sciences, have reported the discovery of multiple plant enzymes—hispidin synthases—that can perform the most complex reaction of the bioluminescence pathway. This discovery is a significant milestone toward figuring out whether plants … Read more
Scientists at CSIRO, Australia’s national science agency, have achieved a breakthrough in molecular plant pathology, marking a technological leap forward for breeding durable disease-resistant crops. Plant pathogens—organisms which cause plant diseases—greatly reduce agricultural productivity and are a persistent threat to global food security. Annually, rust pathogens lead to crop losses of US $1 billion worldwide. … Read more
Nitrogenases are considered promising candidates for the sustainable enzymatic production of ammonia and carbon compounds. Unfortunately, one bottleneck in this complex process, the supply of electrons to the enzymes, has remained a mystery until now. A team at the Max Planck Institute for Terrestrial Microbiology in Marburg has discovered two essential electron carriers that play … Read more
In a recent study published in Science Advances, researchers from the Universities of Bristol and Ghent advocate for a shift in the approach to biological design. The study, titled “Open-endedness in synthetic biology: a route to continual innovation for biological design,” underscores the importance of embracing the idiosyncrasies of biological systems over a rigid focus … Read more
The cell membrane, often referred to as the plasma membrane, stands as a critical component in the realm of biology, serving as a protective barrier that encapsulates the internal environment of cells. Its intricate structure and dynamic functions are integral to the survival and functionality of living organisms. This semi-permeable boundary is a mosaic of … Read more
Molecular biology is a branch of biology that explores the structure, function, and interactions of molecules that make up the essential components of living organisms. It delves into the molecular mechanisms underlying various biological processes, including DNA replication, transcription, translation, and cellular signaling. At its core, molecular biology seeks to understand the molecular basis of … Read more
Biophysics is an interdisciplinary field that merges principles from physics and biology to investigate the physical mechanisms underlying biological processes. This dynamic branch of science employs quantitative and analytical approaches to unravel the mysteries of life, exploring how physical forces, energy, and structure govern the behavior of biological systems. Biophysics spans a wide range of … Read more
Biology is the scientific study of life and living organisms. It explores a vast range of topics, including the structure, function, growth, origin, evolution, and distribution of living organisms. This discipline delves into various levels of biological organization, from molecules and cells to organisms and ecosystems. Through methods like observation, experimentation, and analysis, biologists seek … Read more
Extrachromosomal DNA refers to genetic material that exists outside the chromosomes within a cell. While the majority of an organism’s genetic information is typically organized within the chromosomes in the nucleus, extrachromosomal DNA can be found in various cellular compartments, such as organelles or plasmids. Understanding the role and characteristics of extrachromosomal DNA is crucial … Read more