In recent years, global environmental concerns have prompted a significant shift toward eco-friendly manufacturing processes in organic synthetic chemistry. One such advancement is the use of photoredox catalytic reactions, which leverage light to drive redox reactions via a photoredox catalyst. This method reduces the reliance on harsh and toxic reagents, utilizing visible light as a … Read more
In organic chemistry, π-stacking systems are supramolecular structures that arise due to the dispersion force, a type of intermolecular noncovalent interaction. They are a common occurrence in nature. The stabilized structure of DNA is a very prominent example of a π-stacking system, and so are the arrangement of amino acids in certain proteins. Interestingly, π-stacking … Read more
In a significant advancement for drug research and chemical synthesis, a team of chemists at the University of Münster has devised a new method to precisely integrate the biologically significant difluoromethyl group into pyridines at specific sites. The difluoromethyl group, composed of carbon, two fluorine atoms, and a hydrogen atom, is crucial for determining the … Read more
Astrobiology, a multidisciplinary field at the intersection of astronomy, biology, chemistry, geology, and planetary science, explores the origins, evolution, distribution, and potential for life in the universe. This fascinating realm of scientific inquiry delves into fundamental questions about the nature of life, its cosmic origins, and the conditions required for habitability beyond Earth. From the … Read more
Organic chemistry is the branch of chemistry that deals with the study of carbon-containing compounds. It is a vast and diverse field with applications ranging from pharmaceuticals and materials science to agriculture and environmental science. The study of organic chemistry dates back centuries, with significant advancements made in understanding the structure, properties, and reactions of … Read more
Chemistry, often referred to as the central science, is a branch of natural science that explores the properties, composition, structure, reactions, and changes of matter. It is a discipline that delves into the microscopic realm of atoms and molecules, seeking to understand the fundamental principles that govern the behavior of substances and their transformations. Chemistry … Read more
Researchers, led by Tan Li from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, have made significant strides in identifying potential therapeutic avenues for ovarian cancer. They developed novel small molecule inhibitors targeting CPSF3, a critical component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a pivotal role … Read more
Organic synthesis represents the intricate craft of crafting molecules, serving as the foundation for producing vital commodities like pharmaceuticals, agrochemicals, and materials that fuel cutting-edge devices such as smartphones. It’s akin to a microscopic game of LEGO, where chemists interlock fundamental building blocks to construct intricate molecules, akin to joining LEGO bricks to form complex … Read more
In a recent publication in Nature Neuroscience, dated September 14th, Dr. Chen Yelin and a team of researchers from the Shanghai Institute of Organic Chemistry at the Chinese Academy of Sciences revealed an important discovery. They showed that a specific component of the N-methyl-d-aspartic acid (NMDA) receptor, known as GluN2A, plays a crucial role in … Read more
A groundbreaking research endeavor led by Professor Huang Hanmin’s team at the University of Science and Technology of China (USTC), part of the Chinese Academy of Sciences (CAS), has unveiled a novel concept in metal electron-shuttle catalysis. This pioneering approach has been harnessed to achieve the previously elusive alkylative aminomethylation of unactivated alkenes, marking a … Read more
Exploring the realm of organic chemistry within the vast expanse of interstellar space holds immense significance. It not only deepens our grasp of universal chemistry but also sheds light on the origins of life on Earth and the tantalizing prospects of life elsewhere. The roster of organic compounds detected in space, along with our comprehension … Read more
Hydrogen is considered a promising energy source for the future, provided it is produced in an environmentally friendly manner. It also plays a significant role in the production of essential substances and active ingredients. However, splitting water molecules (H2O) into hydrogen gas (H2) and oxygen presents a significant challenge due to the stability of water. … Read more
An international team of scientists has utilized NASA’s James Webb Space Telescope to make a groundbreaking finding in space. They have successfully detected a novel carbon compound called methyl cation (CH3+) for the first time. This significant discovery took place in a young star system named d203-506, situated approximately 1,350 light-years away within the Orion … Read more
Researchers at the University of Illinois have developed a sustainable method for forming carbon-carbon bonds without the need for expensive and rare metal catalysts. The interdisciplinary team of plasma engineers, chemists, and bioengineers used electricity and a plasma-liquid process to generate solvated electrons, which were then used to facilitate carbon-carbon bond formation in a pinacol … Read more
A team of researchers, led by Prof. Tian Jia from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, has made a significant breakthrough in the field of carbon dioxide (CO2) conversion. Their work, published in Nature Catalysis on May 18, details a novel strategy for selectively converting CO2 using visible light, … Read more
A fascinating discovery has been made by a research team from the universities of Hannover and Würzburg regarding the remarkable Triphyophyllum peltatum, a tropical plant found in West Africa. This plant has attracted considerable attention not only in the field of medical and pharmaceutical research but also from a botanical standpoint. Triphyophyllum peltatum possesses unique … Read more